On a Friday night at Los Angeles discotheque the Zoo, everyone’s got his own agenda. Blue-collar type Gus (Chuck Sacci) is meeting a blind date. Underage girls Jeannie (Terri Nunn) and Frannie (Valerie Landsburg) sneak in, hoping to win a dance contest. Lecherous club owner Tony Di Marco (Jeff Goldblum) makes wagers with his DJ (Ray Vitte) on which married women he can seduce. Meanwhile, the Commodores are set to play, but aspiring singer Nicole (Donna Summer) is hoping to steal the show.

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The film contains many popular disco songs, with many key performers featured, including Donna Summer, Pattie Brooks, Love & Kisses, The Commodores. A triple album containing many of the tracks heard in the film was released six weeks in advance of the theatrical release to build up interest in the film.[19] Several songs heard in the film were not included on the soundtrack album, including Alec R. Costandinos’ “Romeo and Juliet”, Giorgio Moroder’s “From Here to Eternity”, The Originals’ “Down to Love Town”, D.C. LaRue’s “You Can Always Tell a Lady (By the Company She Keeps)”, The Commodores’ “Brick House”, The 5th Dimension’s “You Are The Reason (I Feel Like Dancing)”, Meco’s “Meco’s Theme” and the Village People tracks, “In Hollywood (Everybody Is A Star)” and “I Am What I Am”. The biggest hit single on the album was Donna Summer’s “Last Dance”, which won an Academy Award as well as a Golden Globe for Best Original Song and also made it to #3 on the US singles chart. The song was written by Paul Jabara, who the following year composed Summer’s duet with Barbra Streisand, “No More Tears (Enough Is Enough)”. Jabara performed two of the songs on the Thank God It’s Friday soundtrack and appeared in the film as well.